DGAP-Stimmrechtsanteile: SYGNIS AG

DGAP-PVR: SYGNIS AG: Release according to Article 26, Section 1 of the WpHG [the German Securities Trading Act] with the objective of Europe-wide distribution

SYGNIS AG

24.10.2016 16:00

Dissemination of a Voting Rights Announcement, transmitted by DGAP - a service of EQS Group AG. The issuer is solely responsible for the content of this announcement. ---------------------------------------------------------------------------

Notification of Major Holdings

1. Details of issuer

SYGNIS AG Waldhofer Str. 104 69123 Heidelberg Germany

2. Reason for notification

Acquisition/disposal of shares with voting rights Acquisition/disposal of instruments X Change of breakdown of voting rights Other reason:

3. Details of person subject to the notification obligation

Name: City and country of registered office: Mr Berthold Wipfler

4. Names of shareholder(s) holding directly 3% or more voting rights, if different from 3.

dievini Hopp BioTech holding GmbH & Co. KG

5. Date on which threshold was crossed or reached

19 Oct 2016

6. Total positions

% of voting % of voting rights total of total number rights attached through instruments both in % of voting to shares (total (total of 7.b.1 + (7.a. + rights of of 7.a.) 7.b.2) 7.b.) issuer Result- 3.07 % 0.00 % 3.07 % 37341980 ing situat- ion Previo- 8.62 % n/a % n/a % / us notifi- cation

7. Notified details of the resulting situation a. Voting rights attached to shares (Sec.s 21, 22 WpHG)

ISIN absolute in % direct (Sec. indirect (Sec. direct (Sec. indirect 21 WpHG) 22 WpHG) 21 WpHG) (Sec. 22 WpHG) DE000A1RFM03 0 1146950 0 % 3.07 % Total 1146950 3.07 %

b.1. Instruments according to Sec. 25 para. 1 No. 1 WpHG

Type of Expiration or Exercise or Voting Voting instrument maturity date conversion rights rights in period absolute % % Total %

b.2. Instruments according to Sec. 25 para. 1 No. 2 WpHG

Type of Expiration Exercise or Cash or Voting Voting instrume- or maturity conversion physical rights rights nt date period settlement absolute in % % Total %

8. Information in relation to the person subject to the notification obligation

Person subject to the notification obligation is not controlled and does itself not control any other undertaking(s) holding directly or indirectly an interest in the (underlying) issuer (1.). X Full chain of controlled undertakings starting with the ultimate controlling natural person or legal entity:

Name % of voting % of voting rights Total of both rights (if at through instruments (if (if at least least held 3% or at least held 5% or held 5% or more) more) more) Herr Berthold - % - % - % Wipfler BW Verwaltungs - % - % - % GmbH DH-Capital - % - % - % GmbH & Co. KG dievini Hopp 3.07 % - % - % BioTech holding GmbH & Co. KG Herr Berthold - % - % - % Wipfler BW Verwaltungs - % - % - % GmbH OH - % - % - % Beteiligungen GmbH & Co. KG dievini Hopp 3.07 % - % - % BioTech holding GmbH & Co. KG Herr Berthold - % - % - % Wipfler BW Verwaltungs - % - % - % GmbH OH-Capital - % - % - % GmbH & Co. KG OH - % - % - % Beteiligungen GmbH & Co. KG dievini Hopp 3.07 % - % - % BioTech holding GmbH & Co. KG

9. In case of proxy voting according to Sec. 22 para. 3 WpHG

Date of general meeting: Holding position after general meeting: % (equals voting rights)

10. Other explanatory remarks:



24.10.2016 The DGAP Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases. Archive at www.dgap.de

--------------------------------------------------------------------------- Language: English Company: SYGNIS AG Waldhofer Str. 104 69123 Heidelberg Germany Internet: www.sygnis.com End of Announcement DGAP News-Service ---------------------------------------------------------------------------