Press Release: Novartis presents new data -2-

patients and physicians in multiple disease areas, including Multiple

Sclerosis (MS), Alzheimer's disease, Parkinson's disease, Epilepsy and

Attention Deficit Hyperactivity Disorder, and have a promising pipeline

in MS, Alzheimer's disease, migraine and specialty neurology (e.g.,

neuropathic pain).

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About Novartis

Novartis provides innovative healthcare solutions that address the

evolving needs of patients and societies. Headquartered in Basel,

Switzerland, Novartis offers a diversified portfolio to best meet these

needs: innovative medicines, cost-saving generic and biosimilar

pharmaceuticals and eye care. Novartis has leading positions globally in

each of these areas. In 2017, the Group achieved net sales of USD 49.1

billion, while R&D throughout the Group amounted to approximately USD

9.0 billion. Novartis Group companies employ approximately 124,000

full-time-equivalent associates. Novartis products are sold in

approximately 155 countries around the world. For more information,

please visit http://www.novartis.com.

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References

[1] Tepper S, et al. Assessment of the Long-Term Safety and Efficacy

of Erenumab During Open-Label Treatment of Subjects With Chronic

Migraine. Data presented at 60th Annual Scientific Meeting of the

American Headache Society, San Francisco, June 2018

[2] Ashina M, et al. Long-term Safety and Tolerability of Erenumab:

Three-plus Year Results from an Ongoing Open-Label Extension Study in

Episodic Migraine. Data presented at 60th Annual Scientific Meeting of

the American Headache Society, San Francisco, 30 June 2018

[3] Migraine Research Foundation. Migraine Fact Sheet. 2015.

http://www.migraineresearchfoundation.org/fact-sheet.html. Accessed May

2018

[4] National Institute for Neurological Disorders and Stroke.

https://www.ninds.nih.gov/Disorders/All-Disorders/Migraine-Information-Page

(link is external). Accessed March 2018

[5] World Health Organization. Headache disorders.

http://www.who.int/mediacentre/factsheets/fs277/en/ (link is external).

Accessed May 2018

[6] Global Health Estimates 2015: Disease burden by Cause, Age, Sex,

by Country and by Region, 2000-2015. Geneva, World Health Organization;

2016.

[7] Diamond S et al. Patterns of Diagnosis and Acute and Preventive

Treatment for Migraine in the United States: Results from the American

Migraine Prevalence and Prevention Study. Headache. 2007;47(3):355-63.

[8] Blumenfeld AM et al. Patterns of use and reasons for

discontinuation of prophylactic medications for episodic migraine and

chronic migraine: results from the second international burden of

migraine study (IBMS-II). Headache. 2013 Apr;53(4):644-55.

# # #

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(END) Dow Jones Newswires

June 28, 2018 16:30 ET (20:30 GMT)