Genomic Vision: Molecular Combing Featured in an Oral Presentation on CRISPR/Cas9 Gene Editing at the 3rd CSHL Meeting in New York

Regulatory News:

Genomic Vision (Paris:GV) (FR0011799907 – GV), a company specialized in the development of diagnostic solutions for early cancer detection, genetic diseases and tools for life sciences research, today announced that the result of its collaboration with one of the leading genome editing companies has been presented during an oral presentation* at the 3^rd Cold Spring Harbor Laboratory Meeting (CSHL) on Genome Engineering, held from July 21 to 23, 2017 in Cold Spring Harbor (NY).

In this collaboration, molecular combing was used to characterize the type and the frequency of DNA rearrangements formed as a result of CRISPR/Cas9-mediated gene editing on two disease loci. The results obtained with molecular combing complemented those provided by other approaches and contributed to a more comprehensive safety evaluation of the editing protocols.

Dr Lucia Cinque, Director of Product Innovation at Genomic Vision and co-author of the presentation, says: "The results of this study further reinforce our belief in the value of molecular combing for the development of safe genome editing applications. This is particularly important for therapeutic use, where quantification of rearrangements coupled with a thorough characterization of the ensuing cellular response is critical. This fruitful collaboration has not only shown the potential of molecular combing to leading experts in the field; it has also enabled Genomic Vision to promptly initiate key product improvements in order to facilitate a more wide-spread adoption of its technology as one of the essential tools for the quality and safety control of advanced genome editors.”

* Presentation Title: "Characterization of genomic rearrangements in response to CRISPR/Cas9-induced double strand breaks”(https://meetings.cshl.edu/abstracts.aspx?meet=CRISPR&year=17)

ABOUT GENOMIC VISION

GENOMIC VISION is a company specialized in the development of diagnostic solutions for early cancer detection, genetic diseases and tools for life sciences research. Through the DNA Molecular Combing, a versatile technology allowing to identify genetic abnormalities, GENOMIC VISION stimulates the R&D productivity of the pharmaceutical companies, the leaders of the diagnostic industry and the research labs. The Company develops a robust portfolio of diagnostic tests (breast, ovarian and colorectal cancers, myopathies) and analysis tools (DNA replication, biomarkers discovery, gene editing quality control). Based near Paris, in Bagneux, the Company has approximately 55 employees. GENOMIC VISION is a public listed company listed in compartment C of Euronext’s regulated market in Paris (Euronext: GV - ISIN: FR0011799907). For further information, please visit www.genomicvision.com

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