Genomic Vision Selected for the Horizon 2020 Program’s ‘BeyondSeq’ Project with a Total Grant of €6 Million

Regulatory News:

Genomic Vision (Paris:GV) (FR0011799907 – GV), a molecular diagnostics company specialized in the development of diagnostic tests for genetic diseases and cancers based on molecular combing, today announces that it has been selected to take part in the BeyondSeq (Genomic diagnostics beyond the sequence) project, which has won a highly-selective tender within the framework of Horizon 2020, the European Commission’s program aimed at supporting research and innovation. This project, coordinated by Tel Aviv University, brings together 6 other participants, including a British company and Swedish, Israeli, British and Belgian universities.

The goal of the BeyondSeq project, with a total budget of €6 million until 2019, is to bridge the technological gap between cytogenetic diagnostics, which can identify chromosomal aberrations, and next generation sequencing (NGS), which can detect single base-pair mutations. Genomic Vision’s molecular combing technology perfectly meets this need, by making it possible to visualize single DNA molecules with a high definition and thus identify structural variations in the genome, which are the cause of numerous serious pathologies, and notably certain hereditary types of cancer.

The mission of the participants in this project will be to develop a set of tools, from systems for extracting long DNA molecules and preparing samples through to analysis software to interpret genetic information.

Applications will address a number of indications such as bacterial infections and antibiotic resistance, hematological malignancies, early diagnosis of colorectal and lung cancer, as well as Spinal Muscular Atrophy (SMA). Genomic Vision will thus bring its expertise in the detection of structural variations involved in SMA (deletion of both copies of the SMN 1 gene), and will notably be responsible for developing a test that is capable of identifying "2+0” carriers (carriers of both copies of the SMN 1 gene on a chromosome), which are undetectable using existing techniques.

Yuval Ebenstein, the project’s coordinator at Tel Aviv University, says: "BeyondSeq is a project that is emblematic of European genetic research, whose objective is to develop new technologies to provide complementary solutions to sequencing and thus analyze the hidden dimension of genetic mutations. Our workgroup consists of experts in this field, and we are delighted that a company such as Genomic Vision – with its unique molecular combing technology that is capable of studying individual DNA molecules – should be a part of it.”

Aaron Bensimon, Genomic Vision’s co-founder and Chairman, adds: "As a world leader in the manipulation of individual molecules of DNA, it is totally natural that Genomic Vision should take part in this ambitious research project. This collaboration is completely in line with the technological development strategy that we are implementing in accordance with the commitments we made at the time of our IPO. Genomic Vision will provide this prestigious consortium with its industrial experience while benefiting from the consortium’s academic know-how in order to drive its technology forward towards a new generation of molecular combing.”

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ABOUT GENOMIC VISION

Founded in 2004, Genomic Vision is a molecular diagnostics company specialized in the development of diagnostic tests for genetic diseases and cancers based on molecular combing. Using this innovative technology that allows the direct visualization of individual DNA molecules, Genomic Vision detects quantitative and qualitative variations in the genome that are at the origin of numerous serious pathologies. The Company is developing a solid portfolio of tests that notably target breast cancer and cancer of the colon. Since 2013, the Company has marketed the CombHeliX FSHD test for identifying a myopathy that is difficult to detect, Facio-scapulo-humeral dystrophy (FSHD), in the United States thanks to a strategic alliance with Quest Diagnostics, the American leader in diagnostic laboratory tests, and in France. Genomic Vision has been listed on Compartment C of Euronext Paris since April 2014.

ABOUT MOLECULAR COMBING

DNA molecular combing technology considerably improves the structural and functional analysis of DNA molecules. DNA fibers are stretched out on glass slides, as if "combed”, and uniformly aligned over the whole surface. It is then possible to identify genetic anomalies by locating genes or specific sequences in a patient’s genome using genetic markers, an approach developed by Genomic Vision and patented under the name Genomic Morse Code. This exploration of the entire genome at high resolution via a simple analysis enables the direct visualization of genetic anomalies that are undetectable by other technologies.

For further information, please go to www.genomicvision.com

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DISCLAIMER

This press release contains certain forward-looking statements concerning Genomic Vision and its business.

Such forward-looking statements are based on assumptions that Genomic Vision considers to be reasonable. However, there can be no assurance that such forward-looking statements will be verified, which statements are subject to numerous risks, including the risks set forth in the prospectus on which the French Financial Market Authority (AMF) granted its visa n° 14-087 on March 19, 2014 and to the development of economic conditions, financial markets and the markets in which Genomic Vision operates. The forward-looking statements contained in this press release are also subject to risks not yet known to Genomic Vision or not currently considered material by Genomic Vision. The occurrence of all or part of such risks could cause actual results, financial conditions, performance or achievements of Genomic Vision to be materially different from such forward-looking statements.

This press release and the information contained herein do not constitute and should not be construed as an offer or an invitation to sell or subscribe, or the solicitation of any order or invitation to purchase or subscribe for GENOMIC VISION shares in any country. The distribution of this press release in certain countries may be a breach of applicable laws. The persons in possession of this press release must inquire about any local restrictions and comply with these restrictions.

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