Heat Biologics Closes Enrollment Of Phase 1 Trial Of Vesigenurtacel-L

(RTTNews) - Heat Biologics Inc.(HTBX) announced that it has dosed the ninth and final patient required in the Phase 1 portion of its Phase 1/2 clinical study for Vesigenurtacel-L (HS-410) in patients with high-risk non-muscle invasive bladder cancer.

The company expects to commence the Phase 2 portion of the bladder cancer clinical trial during the fourth quarter of 2014.

Heat recently modified the Phase 1/2 Vesigenurtacel-L study treatment regimen to include a more robust dose-response analysis and the expedited advancement into Phase 2 trials following completed enrollment of a single cohort of Phase 1 data.

Patient enrollment and dosing in the Vesigenurtacel-L Phase 2 study for the treatment of bladder cancer is expected to be completed in the third quarter of 2015. Heat then anticipates reporting top-line recurrence-free survival results in the third quarter of 2016 after the protocol's twelve-month patient observation period ends.