Microbial Products: Technologies, Applications and Global Markets

NEW YORK, Aug. 12, 2013 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

Microbial Products: Technologies, Applications and Global Markets
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This report identifies microbial technologies and applications that have the greatest commercial potential in the 2013 through 2018 time frame. It identifies market drivers, evaluates obstacles to their successful commercialization, and projects future sales of each application. These applications include agricultural, healthcare, manufacturing, energy and environmental applications.

Use this report to:

- Evaluate actual and potential markets for microbes and microbial products in terms of specific application sectors and subsectors.
- Assess the current state of art of technology in microbes and microbial products market.
- Identify the findings and conclusions of microbes and microbial products market, based on information gathered from developers, vendors, and users of microbial products for commercial applications.

Highlights

- The total global market for microbes and microbial products was worth more than $117 billion in 2012. The 2013 market is projected to approach $134 billion, and, by 2018, $179 billion, with a projected five year compound annual growth rate (CAGR) of 6%.
- The microbial products market was worth more than $114 billion in 2012 and is expected to be more than $130 billion in 2013 and $174 billion by 2018, a CAGR of 6%.
- The market for microbes totaled $3.3 billion in 2012. This market is projected to approach nearly $3.6 billion in 2013 and nearly $5.2 billion in 2018 with a CAGR of 7.7%.

STUDY BACKGROUND

A microbe is a minute living organism, such as a bacterium, yeast, or fungus. The first commercial applications of microbes date back to around 1750 BC, when the ancient Sumerians used yeast to brew beer. Microbes were used for centuries to produce bread, wine, vinegar and other common products—without anyone knowing the scientific basis for the ingredient. The systematic study of microbes began in the 17th century with the work of scientists like Antonie Van Leeuwenhoek and Robert Hooke. However, the discipline known today as microbiology was not established until the late 19th century through the work of pioneers like Louis Pasteur, Robert Koch, Martinus Beijerinck and Sergei Winogradsky. The technology related to microbial production of metabolites such as ethanol, lactic acid, butanol, riboflavin, etc. and enzymes such as protease, amylase and invertase were developed as early as the first few decades of the 20th century. Large-scale production of the antibiotic penicillin from Penicillium fungi was perfected during World War II and the microbial production of other antibiotics, amino acids, nucleotides, enzymes and such soon followed. Today, genetically engineered microbes are used for the commercial production of nonmicrobial products such as insulin, interferon, human growth hormone and viral vaccines. Microbes are also used to produce energy (e.g., biodiesel and bioethanol) and to clean up environmental pollutants such as sewage and oil spills. As the active ingredient in biofertilizers and biopesticides, microbes contribute to increasing agricultural productivity, and microbes form the basis of cost-effective methods of mining and metallurgy

STUDY GOALS AND OBJECTIVES

Yet all this seems to be only the beginning: The commercial possibilities of microbes are seemingly endless. However, intuition alone tells us that not all of these technological possibilities are likely to become commercial realities. This report is an update of an earlier BCC Research report published in 2011. Its goal is to survey microbial applications in a wide range of fields based on the most recent data, identify the applications that appear to have significant commercial potential in the near- to mid-term and to develop quantitative estimates of their current and/or future sales. The updated report's specific objectives support this broad goal. These objectives include identifying microbial technologies and applications that have the greatest commercial potential in the 2013 through 2018 time frame, identifying market drivers, evaluating obstacles to their successful commercialization, and projecting future sales of each application.

INTENDED AUDIENCE

This report is intended especially for biotechnology marketing executives, entrepreneurs, investors, venture capitalists and other readers with a need to know where the market for microbial technologies and products is headed over the next five years. Although the report focuses on specific technologies, it is largely non-technical in nature. That is, it is concerned less with theory and jargon than with what works and how much of it the market is likely to purchase. As such, the report's main audience is executive management, marketing, and financial analysts. It is not written specifically for scientists and technologists, although its findings concerning the market for their work, and by extension the availability of government and corporate research funding for different technologies and applications, should interest them as well

SCOPE AND FORMAT

This report addresses the global market for microbes and microbial products used in commercial applications during the period from 2012 through 2018. These applications include agricultural, healthcare, manufacturing, energy and environmental applications. Viruses are sometimes classified as microbes, but this report excludes them because they are non-living. The format of this study includes the following major elements:
- Summary.
- Definitions.
- Description of microbes.
- End uses and applications of microbes.
- Regulation.
- Recent technological developments.
- Market size and segmentation, 2012 to 2018.
- Company profiles.
- Key patents.

INFORMATION SOURCES AND METHODOLOGY

Both primary and secondary research methodologies were used in preparing this study. The findings and conclusions of this report are based on information gathered from developers, vendors, and users of microbial products for commercial applications. Interview data were combined with information gathered through an extensive review of secondary sources such as trade publications, trade associations, company literature, and online databases to produce the baseline market estimates contained in this report. The base year for analysis and projection is 2012. With 2012 as a baseline, market projections were developed for 2013 through 2018. The projections are based on a combination of a consensus among the primary contacts combined with BCC's understanding of the key market drivers and their impact from a historical and an analytical perspective. The specific assumptions and the approach BCC used to develop the projections (both near/mid-term and long term) for each application are documented in detail under the various segments addressed. This way, readers can see how the market estimates were developed and, if they so desire, can test the impact on the final numbers of changing assumptions regarding matters such as the date of regulatory approval. All dollar projections presented in this report are in 2012 constant dollars.

CHAPTER 1 INTRODUCTION 2
STUDY BACKGROUND 2
STUDY GOALS AND OBJECTIVES 2
INTENDED AUDIENCE 3
SCOPE AND FORMAT 3

INFORMATION SOURCES
AND METHODOLOGY 3
ANALYST CREDENTIALS 4
RELATED BCC RESEARCH REPORTS 4
BCC ON-LINE SERVICES 5
DISCLAIMER 5
CHAPTER 2 EXECUTIVE SUMMARY 7
SUMMARY TABLE GLOBAL MARKET FOR MICROBES AND MICROBIAL PRODUCTS
THROUGH 2018 ($ MILLIONS) 7
SUMMARY FIGURE TRENDS IN GLOBAL MARKET FOR MICROBES AND MICROBIAL
PRODUCTS, 2012-2018 ($ MILLIONS) 7
CHAPTER 3 OVERVIEW 10
GENERAL DESCRIPTION OF MICROBES 10
DEFINITIONS 10
Microbes 10
Bacteria 10
Fungi 10
Archaea 10
Protists 11
Micro-Animals and Micro-Plants 11
Commercial Microbes 11
Microbial Products 11
PROPERTIES 12
Temperature Range 12
TABLE 1 MICROBE TEMPERATURE RANGES 12
Psychrophiles 12
Mesophiles 13
Thermophiles and Hyperthermophiles 13
Acidity 13
Osmotic Pressure 14
Oxygen 14
Water 15
Metabolite Production 15
OCCURRENCE AND PRODUCTION 15
Habitats 15
Culture 16
Isolation 16
Sterilization 16
Culture 16
Genetic Engineering 17
HISTORY 17
END USES AND APPLICATIONS 19
TABLE 2 END USES/APPLICATIONS OF COMMERCIAL MICROBES 20
AGRICULTURE 20
HEALTHCARE 20
MANUFACTURING 21
ENERGY 21
ENVIRONMENT 21
MARKET SIZE AND SEGMENTATION 22
MARKET SIZE AND GROWTH TRENDS 22
FIGURE 1 GLOBAL MARKET TRENDS FOR MICROBIAL PRODUCTS 2012–2018 ($
BILLIONS) 22
END USES 22
TABLE 3 GLOBAL MARKET FOR MICROBIAL PRODUCTS BY END-USE SECTOR
THROUGH 2018 ($ MILLIONS) 23
FIGURE 2 GLOBAL MARKET FOR MICROBES AND MICROBIAL PRODUCTS BY
END-USE SECTOR, 2012-2018 (%) 23
CHAPTER 4 AGRICULTURAL MARKET FOR MICROBES AND MICROBIAL PRODUCTS 26
SUMMARY 26
FIGURE 3 GLOBAL AGRICULTURAL MARKETS FOR PRODUCTS MADE FROM
MICROBES BY APPLICATION TYPE, 2012–2018 ($ MILLIONS) 26
TABLE 4 GLOBAL AGRICULTURAL MARKETS FOR PRODUCTS MADE FROM
MICROBES BY APPLICATION TYPE, THROUGH 2018 ($ MILLIONS) 27
FIGURE 4 GLOBAL MARKET SHARES OF AGRICULTURAL PRODUCTS MADE FROM
MICROBES BY APPLICATION, 2012-2018 (%) 27
MICROBIAL PESTICIDES 28
TYPES OF MICROBIAL PESTICIDES 28
Bacteria 28
Bacillus thuringiensis 28
"Milky Spore" 29
Agrobacterium Radiobacter 30
Fungi 31
Beauveria bassiana 31
Verticillium Lecanii 31
Lagenidium giganteum 32
Other Fungi 32
Protozoa 32
Nosema Locustae 32
Nematodes 33
Steinernema Feltiae 33
Steinernema Scapterisci 34
Steinernema Riobravis 34
Steinernema Carpocapsae 34
Heterorhabditis Bacteriophora 34
Heterorhabditis Indica 34
Heterorhabditis Megidis 35
SUPPLIERS 35
TABLE 5 SUPPLIERS OF MICROBIAL PESTICIDES 35
MARKETS 36
FIGURE 5 GLOBAL MICROBIAL PESTICIDE MARKET BY SEGMENT, 2012 (%) 36
TABLE 6 PROJECTED GLOBAL SALES OF MICROBIAL PESTICIDES BY SEGMENT
THROUGH 2018 ($ MILLIONS) 37
Bacterial Biopesticides 37
FIGURE 6 GLOBAL TRENDS IN ORGANICALLY FARMED AREAS 2005-2018 (MILLION
HECTARES) 37
TABLE 7 PROJECTED GLOBAL SALES OF BACTERIAL BIOPESTICIDES, THROUGH
2018 ($ MILLIONS) 38
Other Biopesticides 38
MICROBIAL FERTILIZERS 38
TYPES OF BIOFERTILIZERS 39
Nitrogen Biofertilizers 39
Rhizobium 39
Azospirillum 39
Azotobacter 40
Blue-Green Algae 40
Phosphorus 40
Phosphate Solubilizing Microorganisms 40
Compost Treatment 41
Cellulolytic Fungal Culture 41
SUPPLIERS 41
TABLE 8 SUPPLIERS OF BIOFERTILIZERS 41
MARKETS 42
TABLE 9 PROJECTED GLOBAL SALES OF MICROBIAL FERTILIZERS BY SEGMENT,
THROUGH 2018 ($ MILLIONS) 42
ANIMAL FEED ADDITIVES 43
TYPES OF MICROBIAL ANIMAL FEED 43
Bacteria 43
Algae 43
SUPPLIERS 43
TABLE 10 SUPPLIERS OF MICROBIAL ANIMAL AND FISH FEED ADDITIVES 44
MARKETS 44
TABLE 11 PROJECTED GLOBAL SALES OF MICROBIAL FEED SUPPLEMENTS,
THROUGH 2018 ($ MILLIONS) 44
CHAPTER 5 HEALTHCARE MARKET FOR MICROBES AND MICROBIAL PRODUCTS 47
SUMMARY 47
FIGURE 7 GLOBAL MARKETS FOR MICROBES AND MICROBIAL PRODUCTS USED IN
HEALTHCARE APPLICATIONS, 2012-2018 ($ MILLIONS) 47
TABLE 12 GLOBAL HEALTHCARE MARKETS FOR MICROBES AND MICROBIAL
PRODUCTS, THROUGH 2018 ($ MILLIONS) 47
FIGURE 8 GLOBAL HEALTHCARE MARKET FOR MICROBES AND MICROBIAL
PRODUCT SHARES, 2012-2018 (%) 48
MICROBIAL BIOPHARMACEUTICALS 48
TECHNOLOGY 48
Direct Extraction from Natural Sources 49
Recombinant DNA Technology 49
SUPPLIERS 50
TABLE 13 BIOPHARMACEUTICAL SUPPLIERS 50
MARKETS 50
TABLE 14 GLOBAL MARKET FOR MICROBIAL BIOPHARMACEUTICALS, THROUGH
2018 ($ MILLIONS) 51
THERAPEUTICS 51
PROBIOTICS 51
Types of Probiotics 51
Recent Developments 52
New Coating Techniques 52
Suppliers 52
TABLE 15 SELECTED SUPPLIERS OF THERAPEUTIC PROBIOTICS 53
Markets 53
TABLE 16 GLOBAL MARKET FOR PROBIOTICS, THROUGH 2018 ($ MILLIONS) 53
TABLE 17 GLOBAL MARKET FOR PROBIOTICS BY GEOGRAPHIC REGION, THROUGH
2018 ($ MILLIONS) 53
FIGURE 9 GLOBAL MARKET FOR PROBIOTICS BY GEOGRAPHIC REGION, 2012-2018
(%) 54
CHAPTER 6 MANUFACTURING MARKET FOR MICROBES AND MICROBIAL PRODUCTS 56
SUMMARY 56
FIGURE 10 GLOBAL MARKETS FOR MICROBIAL PRODUCTS USED IN
MANUFACTURING APPLICATIONS, 2012–2018 ($ MILLIONS) 56
TABLE 18 GLOBAL MANUFACTURING MARKETS FOR MICROBES AND MICROBIAL
PRODUCTS, 2012–2018 ($ MILLIONS) 57
FIGURE 11 GLOBAL MICROBIAL MANUFACTURING-RELATED PRODUCT MARKET
SHARES, 2012–2018 (%) 57
FOOD PROCESSING 58
TECHNOLOGIES 58
Baking 58
Brewing 58
Winemaking 59
Cultured Dairy Products 59
SUPPLIERS 59
TABLE 19 SELECTED SUPPLIERS OF YEAST AND OTHER FOOD PROCESSING
MICROBES 59
MARKETS 60
TABLE 20 GLOBAL MARKET FOR YEASTS USED IN FOOD PROCESSING, THROUGH
2018 ($ MILLIONS) 60
ENZYMES 60
TECHNOLOGIES 60
APPLICATIONS 61
SUPPLIERS 61
TABLE 21 MANUFACTURERS OF INDUSTRIAL ENZYMES 62
MARKETS 62
TABLE 22 GLOBAL MARKET FOR MICROBIALLY PRODUCED INDUSTRIAL ENZYMES,
THROUGH 2018 ($ MILLIONS) 62
COMMODITY AND SPECIALTY CHEMICALS 62
TECHNOLOGIES 63
Natural Metabolic Products as Commodity Chemicals 63
TABLE 23 REPRESENTATIVE CHEMICALS PRODUCED FROM MICROBES 63
Metabolically Engineered Microbes 63
SUPPLIERS 64
TABLE 24 COMPANIES THAT MICROBIALLY PRODUCE BULK CHEMICALS 65
MARKETS 65
TABLE 25 GLOBAL MARKET FOR MICROBIALLY PRODUCED COMMODITY AND
SPECIALTY CHEMICALS, THROUGH 2018 ($ MILLIONS) 65
BIOPOLYMERS 65
TECHNOLOGIES 65
Polyhydroxyalkanoates 66
Polylactic Acid 66
Hyaluronic Acid 66
Other Microbial Bioplastics 66
Bacterial Cellulose 67
Pullulan 67
Xanthan 67
APPLICATIONS 68
TABLE 26 MICROBIAL BIOPOLYMER APPLICATIONS 68
SUPPLIERS 68
TABLE 27 BIOPOLYMER SUPPLIERS 69
MARKETS 69
TABLE 28 GLOBAL MARKET FOR MICROBIAL BIOPOLYMERS BY TYPE OF POLYMER,
THROUGH 2018 ($ MILLIONS) 70
CHAPTER 7 ENERGY MARKET FOR MICROBES AND MICROBIAL PRODUCTS 72
SUMMARY 72
FIGURE 12 GLOBAL MARKET FOR MICROBES AND MICROBIAL PRODUCTS USED IN
ENERGY APPLICATIONS, 2012–2018 ($ MILLIONS) 72
TABLE 29 GLOBAL ENERGY MARKETS FOR MICROBES AND MICROBIAL PRODUCTS,
THROUGH 2018 ($ MILLIONS) 73
FIGURE 13 GLOBAL MICROBIAL ENERGY-RELATED PRODUCTS SHARES 2012-2018
(%) 73
BIOFUELS PRODUCTION 74
TECHNOLOGY 74
Ethanol 74
Sugar- and Starch-Based Ethanol 74
Cellulosic Ethanol (Bioethanol) 74
Bacterial Bioethanol 75
Fungal Bioethanol 75
Algal Bioethanol 75
Biodiesel 76
Bacterial Biodiesel 76
Algal Biodiesel 76
Fungal Biodiesel 77
APPLICATIONS 78
SUPPLIERS 78
TABLE 30 SUPPLIERS OF ETHANOL AND BIODIESEL PRODUCTS AND
TECHNOLOGIES 79
MARKET 79
TABLE 31 VALUE OF GLOBAL BIOFUELS PRODUCED USING MICROBIAL
TECHNOLOGIES, THROUGH 2018 ($ MILLIONS) 80
Ethanol 80
Starch- and Sugar-Based Ethanol 80
TABLE 32 GLOBAL MICROBIAL PRODUCTION OF STARCH- AND SUGAR-BASED
ETHANOL THROUGH 2018 (MILLIONS; $ MILLIONS) 81
Bioethanol 81TABLE 33 GLOBAL MICROBIAL BIOETHANOL PRODUCTION, THROUGH 2018
(TONS/$ MILLIONS) 81
Biodiesel 82
TABLE 34 GLOBAL MICROBIAL BIODIESEL PRODUCTION, THROUGH 2018 (TONS/$
MILLIONS) 83
MICROBIAL ENHANCED OIL RECOVERY 83
TECHNOLOGY 83
APPLICATIONS 84
SUPPLIERS 84
TABLE 35 SUPPLIERS OF MICROBIAL ENHANCED OIL RECOVERY PRODUCTS AND
SERVICES 85
MARKET 85
TABLE 36 GLOBAL MARKET FOR MICROBIAL ENHANCED OIL RECOVERY PRODUCTS
AND SERVICES, THROUGH 2018 ($ MILLIONS) 85
MICROBIAL FUEL CELLS 86
TECHNOLOGIES 86
Mediator Microbial Fuel Cells 86
Mediator-Less Microbial Fuel Cells 86
Microbial Electrolysis Cells 87
Soil-Based Microbial Fuel Cells 87
Recent Developments 87
Benthic Unattended Generators 87
Granular Activated Carbon-Based MFCs 87
APPLICATIONS 88
SUPPLIERS 89
TABLE 37 SELECTED DEVELOPERS AND SUPPLIERS OF MICROBIAL FUEL CELLS 89
MARKETS 89
TABLE 38 GLOBAL MARKET FOR MICROBIAL FUEL CELLS, THROUGH 2018 ($
MILLIONS) 90
HYDROGEN PRODUCTION 90
TECHNOLOGIES 90
Photobiological Water Splitting 90
"Dark" Fermentation 91
Combined Fermentation 92

SUPPLIERS 92
TABLE 39 SELECTED DEVELOPERS OF MICROBIAL HYDROGEN PRODUCTION
TECHNOLOGIES 92
MARKETS 93
CHAPTER 8 ENVIRONMENTAL MARKET FOR MICROBES AND MICROBIAL PRODUCTS 95
SUMMARY 95
FIGURE 14 GLOBAL MARKETS FOR MICROBIAL PRODUCTS USED IN
ENVIRONMENTAL APPLICATIONS, 2012-2018 ($ MILLIONS) 95
TABLE 40 GLOBAL MARKETS FOR MICROBIAL PRODUCTS USED IN
ENVIRONMENTAL APPLICATIONS, THROUGH 2018 ($ MILLIONS) 96
FIGURE 15 GLOBAL MICROBIAL ENVIRONMENTAL PRODUCT SEGMENTS, 2012-2018
(%) 96
ENVIRONMENTAL MONITORING 97
TECHNOLOGIES 97
Microbial Respiration 97
Microbial Toxic Concentration 98
Biological Oxygen Demand 98
Genetically Engineered Organisms 98
APPLICATIONS 99
SUPPLIERS 99
TABLE 41 SELECTED SUPPLIERS OF MICROBIAL ASSAYS 99
MARKETS 100
TABLE 42 GLOBAL SALES OF MICROBE-BASED BIOSENSORS, THROUGH 2018 ($
MILLIONS) 100
TABLE 43 GLOBAL MARKET FOR MICROBE-BASED BIOSENSORS BY GEOGRAPHIC
REGION, THROUGH 2018 ($ MILLIONS) 100
FIGURE 16 GLOBAL MARKET FOR MICROBE-BASED BIOSENSORS BY GEOGRAPHIC
REGION, 2012-2018 (%) 101
BIOREMEDIATION 101
TECHNOLOGIES 101
In Situ Bioremediation 102
In Situ Bioremediation of Groundwater 102
Direct Groundwater Bioremediation 102
Pumping and On-Site Remediation 102
Ex Situ Bioremediation 102
Bioreactors 102

Enzyme Treatment 103
MARKETS 103
TABLE 44 GLOBAL SALES OF MICROBIAL AND ASSOCIATED BIOREMEDIATION
PRODUCTS, THROUGH 2018 ($ MILLIONS) 104
RECYCLING 104
TECHNOLOGIES 104
Plastic-Eating Bacteria 104
MARKETS 105
OIL SPILLS AND RESIDUES CLEANUP 105
TECHNOLOGIES 105
Oil-Eating Bacterial Preparations 105
Genetically Modified Oil-Degrading Microbes 106
APPLICATIONS 107
SUPPLIERS 107
TABLE 45 SUPPLIERS OF OIL-DEGRADING MICROBES 107
MARKETS 107
TABLE 46 GLOBAL SALES OF OIL-DEGRADING MICROBIAL PRODUCTS, THROUGH
2018 ($ MILLIONS) 108
WASTEWATER/SEWAGE TREATMENT 108
TECHNOLOGIES 108
Public Wastewater and Sewage 108
Cold Weather Bacteria 109
Bacteria for Foaming and Bulking Control 109
Phosphate Reduction and Control 109
Industrial Process Wastes 110
Food Processing Wastes 110
Pulp and Paper Wastewater 110
Other Industrial Wastewater 110
APPLICATIONS 111
SUPPLIERS 111
TABLE 47 SUPPLIERS OF MICROBIAL PRODUCTS FOR WASTEWATER/SEWAGE
TREATMENT 111
MARKETS 112
TABLE 48 GLOBAL SALES OF MICROBIAL WASTEWATER TREATMENT PRODUCTS
USED IN THE PUBLIC AND INDUSTRIAL SEGMENTS, THROUGH 2018 ($ MILLIONS) 112
CHAPTER 9 REGULATION 114
UNITED STATES 114
DEPARTMENT OF AGRICULTURE 114
Animal and Plant Health Inspection Service (APHIS) 114
ENVIRONMENTAL PROTECTION AGENCY 115
Federal Insecticide, Fungicide and Rodenticide Act (FIFRA). 115
Federal Food, Drug and Cosmetics Act as Amended by the Food
Quality Protection Act 115

Toxic Substances Control Act 115
Resource Conservation and Recovery Act and Comprehensive
Environmental Response, Compensation, and Liability Act 116
FOOD AND DRUG ADMINISTRATION 117
Federal Food, Drug, and Cosmetic Act 117
STATE-LEVEL REGULATIONS 118
EUROPEAN UNION 118
DIRECTIVE 98/81/EC ON THE CONTAINED USE OF GENETICALLY MODIFIED
MICROORGANISMS 118
DIRECTIVE 2001/18/EC ON THE DELIBERATE RELEASE INTO THE
ENVIRONMENT OF GMOS 119
REGULATION (EC) NO. 1107/2009 ON THE PLACING OF PLANT
PROTECTION PRODUCTS ON THE MARKET 119
REGULATION (EC) NO 726/2004 ON PROCEDURES FOR THE
AUTHORIZATION AND SUPERVISION OF MEDICINAL PRODUCTS FOR
HUMAN AND VETERINARY USE
119
JAPAN 120
FOOD SANITATION LAW 120
FEED SAFETY LAW 120
OTHER COUNTRIES 120
BRAZIL 121
CHINA 121
INDIA 122
RUSSIA 122
AFRICAN COUNTRIES 122
CHAPTER 10 COMPANY PROFILES 125
AGRICULTURAL APPLICATIONS 125
BIOPESTICIDES 125
AgraQuest, Inc. 125
Certis USA, LLC 125
Laverlam International 125
Valent BioSciences Corp. 126
BIOFERTILIZERS 126
Becker Underwood 126
BioOrganics, Inc. 126
JH Biotech, Inc. 127
Mycorrhizal Applications, Inc. 127
Novozymes Biologicals 127
Ruchi Biochemicals 128
ANIMAL FEED ADDITIVES 128
Earthrise Nutritionals, LLC 128
METabolic EXplorer S.A. 128
Solarium Biotechnology 129
Taiwan Chlorella Manufacturing Co, Ltd. 129
HEALTHCARE APPLICATIONS 130
MICROBIAL BIOPHARMACEUTICALS 130
Amgen Inc. 130
Genzyme Corp. 130
Novo Nordisk A/S 131

PROBIOTICS 131
Ardeypharm GmbH Pharmazeutische Fabrik 131
Osel, Inc. 131
Procter & Gamble Co. 132
Sigma-Tau Pharmaceuticals, Inc. 132
MANUFACTURING APPLICATIONS 132
FOOD PROCESSING 132
AB Mauri 132
Lallemand, Inc. 133
Lesaffre et Compagnie 133
INDUSTRIAL ENZYMES 133
Genencor International, Inc. 133
Novozymes A/S 134
Specialty Enzymes and Biochemicals Co. 134
BULK CHEMICALS 134
Allylix, Inc. 134
Amyris, Inc. 135
Genomatica 135
Gevo 136
MICROBIAL BIOPLASTICS 136
Cereplast, Inc. 136
DURECT Corp. 137
Lone Star Heart, Inc. 137
ENERGY APPLICATIONS 137
BIOFUELS 137
Algae Biosciences Corp. 137
Algenol 138
Amyris, Inc. 138
Coskata, Inc. 138
Desert Sweet Biofuels 139
Energy Derived 139
Iogen Corp. 139
LS9, Inc. 140
PetroSun 140
Qteros, Inc. 141
Sapphire Energy 141
Waltham Technologies 141
XL Renewables, Inc. 142
MICROBIAL ENHANCED OIL RECOVERY 142
Environmental BioTechnologies, Inc. 142
Glori Energy Inc. 142
Microbes Biosciences. 142
Rawwater Engineering Co., Ltd. 143
Synthetic Genomics, Inc. 143
Titan Oil Recovery 144
HYDROGEN PRODUCTION 144
Biohydrogen, Ltd. 144
Nanologix, Inc. 145
Sapporo Breweries, Ltd. 145
Solarvest BioEnergy 146
MICROBIAL FUEL CELLS 146
Cambrian Innovation 146
Emefcy, Ltd. 146
HydroQual, Inc. 147
Hy-SyEnce 147
Microbial Fuel Cell Technologies, LLC 147
Trophos Energy 148
ENVIRONMENTAL APPLICATIONS 148

MICROBIAL ASSAYS 148
CheckLight Ltd. 148
NCIMB, Ltd. 148
BIOREMEDIATION 149
BIO-SYSTEMS International 149
Catalina BioSolutions 149
USA BioProducts Co. 149
OIL-EATING MICROBES 150
Aabaco Industries 150
Altogen Biosystems 150
Bioremediation, Inc. 150
Evolugate, LLC 150
Microbial Discovery Group 151
Microsorb Environmental Products, Inc. 151
Micro-TES, Inc. 151
Osprey Biotechnics 152WASTEWATER/SEWAGE TREATMENT 152
Alken-Murray Corp. 152
Applied Biotech Industries 152
Aquafix, Inc. 153
BioConversion Technology 153
Bio-Systems International 153
Custom Biologicals, Inc. 153
General Environmental Science 154
Natural Environmental Systems, LLC 154
CHAPTER 11 PATENT ANALYSIS 156
FIGURE 17 U.S. MICROBIAL PRODUCT PATENTS BY APPLICATION AREA ISSUED
FROM 1976 THROUGH JUNE 1, 2013 (NUMBER/%) 156
FIGURE 18 TRENDS IN U.S. MICROBIAL PRODUCT PATENTS AWARDED ANNUALLY,
2006-2012 157

LIST OF TABLES

SUMMARY TABLE GLOBAL MARKET FOR MICROBES AND MICROBIAL PRODUCTS
THROUGH 2018 ($ MILLIONS) 7
TABLE 1 MICROBE TEMPERATURE RANGES 12
TABLE 2 END USES/APPLICATIONS OF COMMERCIAL MICROBES 20
TABLE 3 GLOBAL MARKET FOR MICROBIAL PRODUCTS BY END-USE SECTOR
THROUGH 2018 ($ MILLIONS) 23
TABLE 4 GLOBAL AGRICULTURAL MARKETS FOR PRODUCTS MADE FROM MICROBES
BY APPLICATION TYPE, THROUGH 2018 ($ MILLIONS) 27
TABLE 5 SUPPLIERS OF MICROBIAL PESTICIDES 35
TABLE 6 PROJECTED GLOBAL SALES OF MICROBIAL PESTICIDES BY SEGMENT
THROUGH 2018 ($ MILLIONS) 37
TABLE 7 PROJECTED GLOBAL SALES OF BACTERIAL BIOPESTICIDES, THROUGH 2018
($ MILLIONS) 38
TABLE 8 SUPPLIERS OF BIOFERTILIZERS 41
TABLE 9 PROJECTED GLOBAL SALES OF MICROBIAL FERTILIZERS BY SEGMENT,
THROUGH 2018 ($ MILLIONS) 42
TABLE 10 SUPPLIERS OF MICROBIAL ANIMAL AND FISH FEED ADDITIVES 44
TABLE 11 PROJECTED GLOBAL SALES OF MICROBIAL FEED SUPPLEMENTS, THROUGH
2018 ($ MILLIONS) 44
TABLE 12 GLOBAL HEALTHCARE MARKETS FOR MICROBES AND MICROBIAL
PRODUCTS, THROUGH 2018 ($ MILLIONS) 47
TABLE 13 BIOPHARMACEUTICAL SUPPLIERS 50
TABLE 14 GLOBAL MARKET FOR MICROBIAL BIOPHARMACEUTICALS, THROUGH 2018
($ MILLIONS) 51
TABLE 15 SELECTED SUPPLIERS OF THERAPEUTIC PROBIOTICS 53
TABLE 16 GLOBAL MARKET FOR PROBIOTICS, THROUGH 2018 ($ MILLIONS) 53
TABLE 17 GLOBAL MARKET FOR PROBIOTICS BY GEOGRAPHIC REGION, THROUGH
2018 ($ MILLIONS) 53
TABLE 18 GLOBAL MANUFACTURING MARKETS FOR MICROBES AND MICROBIAL
PRODUCTS, 2012–2018 ($ MILLIONS) 57
TABLE 19 SELECTED SUPPLIERS OF YEAST AND OTHER FOOD PROCESSING
MICROBES 59
TABLE 20 GLOBAL MARKET FOR YEASTS USED IN FOOD PROCESSING, THROUGH
2018 ($ MILLIONS) 60
TABLE 21 MANUFACTURERS OF INDUSTRIAL ENZYMES 62
TABLE 22 GLOBAL MARKET FOR MICROBIALLY PRODUCED INDUSTRIAL ENZYMES,
THROUGH 2018 ($ MILLIONS) 62
TABLE 23 REPRESENTATIVE CHEMICALS PRODUCED FROM MICROBES 63
TABLE 24 COMPANIES THAT MICROBIALLY PRODUCE BULK CHEMICALS 65
TABLE 25 GLOBAL MARKET FOR MICROBIALLY PRODUCED COMMODITY AND
SPECIALTY CHEMICALS, THROUGH 2018 ($ MILLIONS) 65
TABLE 26 MICROBIAL BIOPOLYMER APPLICATIONS 68
TABLE 27 BIOPOLYMER SUPPLIERS 69
TABLE 28 GLOBAL MARKET FOR MICROBIAL BIOPOLYMERS BY TYPE OF POLYMER,
THROUGH 2018 ($ MILLIONS) 70
TABLE 29 GLOBAL ENERGY MARKETS FOR MICROBES AND MICROBIAL PRODUCTS,
THROUGH 2018 ($ MILLIONS) 73
TABLE 30 SUPPLIERS OF ETHANOL AND BIODIESEL PRODUCTS AND TECHNOLOGIES 79
TABLE 31 VALUE OF GLOBAL BIOFUELS PRODUCED USING MICROBIAL
TECHNOLOGIES, THROUGH 2018 ($ MILLIONS) 80
TABLE 32 GLOBAL MICROBIAL PRODUCTION OF STARCH- AND SUGAR-BASED
ETHANOL THROUGH 2018 (MILLIONS; $ MILLIONS) 81
TABLE 33 GLOBAL MICROBIAL BIOETHANOL PRODUCTION, THROUGH 2018 (TONS/$
MILLIONS) 81
TABLE 34 GLOBAL MICROBIAL BIODIESEL PRODUCTION, THROUGH 2018 (TONS/$
MILLIONS) 83
TABLE 35 SUPPLIERS OF MICROBIAL ENHANCED OIL RECOVERY PRODUCTS AND
SERVICES 85
TABLE 36 GLOBAL MARKET FOR MICROBIAL ENHANCED OIL RECOVERY PRODUCTS
AND SERVICES, THROUGH 2018 ($ MILLIONS) 85
TABLE 37 SELECTED DEVELOPERS AND SUPPLIERS OF MICROBIAL FUEL CELLS 89
TABLE 38 GLOBAL MARKET FOR MICROBIAL FUEL CELLS, THROUGH 2018 ($
MILLIONS) 90
TABLE 39 SELECTED DEVELOPERS OF MICROBIAL HYDROGEN PRODUCTION
TECHNOLOGIES 92
TABLE 40 GLOBAL MARKETS FOR MICROBIAL PRODUCTS USED IN ENVIRONMENTAL
APPLICATIONS, THROUGH 2018 ($ MILLIONS) 96
TABLE 41 SELECTED SUPPLIERS OF MICROBIAL ASSAYS 99
TABLE 42 GLOBAL SALES OF MICROBE-BASED BIOSENSORS, THROUGH 2018 ($
MILLIONS) 100

TABLE 43 GLOBAL MARKET FOR MICROBE-BASED BIOSENSORS BY GEOGRAPHIC
REGION, THROUGH 2018 ($ MILLIONS) 100
TABLE 44 GLOBAL SALES OF MICROBIAL AND ASSOCIATED BIOREMEDIATION
PRODUCTS, THROUGH 2018 ($ MILLIONS) 104
TABLE 45 SUPPLIERS OF OIL-DEGRADING MICROBES 107
TABLE 46 GLOBAL SALES OF OIL-DEGRADING MICROBIAL PRODUCTS, THROUGH
2018 ($ MILLIONS) 108
TABLE 47 SUPPLIERS OF MICROBIAL PRODUCTS FOR WASTEWATER/SEWAGE
TREATMENT 111
TABLE 48 GLOBAL SALES OF MICROBIAL WASTEWATER TREATMENT PRODUCTS
USED IN THE PUBLIC AND INDUSTRIAL SEGMENTS, THROUGH 2018 ($ MILLIONS) 112
LIST OF FIGURES
SUMMARY FIGURE TRENDS IN GLOBAL MARKET FOR MICROBES AND MICROBIAL
PRODUCTS, 2012-2018 ($ MILLIONS) 7
FIGURE 1 GLOBAL MARKET TRENDS FOR MICROBIAL PRODUCTS 2012–2018 ($
BILLIONS) 22
FIGURE 2 GLOBAL MARKET FOR MICROBES AND MICROBIAL PRODUCTS BY END-USE
SECTOR, 2012-2018 (%) 23
FIGURE 3 GLOBAL AGRICULTURAL MARKETS FOR PRODUCTS MADE FROM
MICROBES BY APPLICATION TYPE, 2012–2018 ($ MILLIONS) 26
FIGURE 4 GLOBAL MARKET SHARES OF AGRICULTURAL PRODUCTS MADE FROM
MICROBES BY APPLICATION, 2012-2018 (%) 27
FIGURE 5 GLOBAL MICROBIAL PESTICIDE MARKET BY SEGMENT, 2012 (%) 36
FIGURE 6 GLOBAL TRENDS IN ORGANICALLY FARMED AREAS 2005-2018 (MILLION
HECTARES) 37
FIGURE 7 GLOBAL MARKETS FOR MICROBES AND MICROBIAL PRODUCTS USED IN
HEALTHCARE APPLICATIONS, 2012-2018 ($ MILLIONS) 47
FIGURE 8 GLOBAL HEALTHCARE MARKET FOR MICROBES AND MICROBIAL PRODUCT
SHARES, 2012-2018 (%) 48
FIGURE 9 GLOBAL MARKET FOR PROBIOTICS BY GEOGRAPHIC REGION, 2012-2018
(%) 54
FIGURE 10 GLOBAL MARKETS FOR MICROBIAL PRODUCTS USED IN MANUFACTURING
APPLICATIONS, 2012–2018 ($ MILLIONS) 56
FIGURE 11 GLOBAL MICROBIAL MANUFACTURING-RELATED PRODUCT MARKET
SHARES, 2012–2018 (%) 57
FIGURE 12 GLOBAL MARKET FOR MICROBES AND MICROBIAL PRODUCTS USED IN
ENERGY APPLICATIONS, 2012–2018 ($ MILLIONS) 72
FIGURE 13 GLOBAL MICROBIAL ENERGY-RELATED PRODUCTS SHARES 2012-2018
(%) 73
FIGURE 14 GLOBAL MARKETS FOR MICROBIAL PRODUCTS USED IN ENVIRONMENTAL
APPLICATIONS, 2012-2018 ($ MILLIONS) 95
FIGURE 15 GLOBAL MICROBIAL ENVIRONMENTAL PRODUCT SEGMENTS, 2012-2018
(%) 96
FIGURE 16 GLOBAL MARKET FOR MICROBE-BASED BIOSENSORS BY GEOGRAPHIC
REGION, 2012-2018 (%) 101
FIGURE 17 U.S. MICROBIAL PRODUCT PATENTS BY APPLICATION AREA ISSUED FROM
1976 THROUGH JUNE 1, 2013 (NUMBER/%) 156
FIGURE 18 TRENDS IN U.S. MICROBIAL PRODUCT PATENTS AWARDED ANNUALLY,
2006-2012 157

To order this report:
Diagnostics Industry: Microbial Products: Technologies, Applications and Global Markets

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