New York, September 16, 2016 -- Moody's Investors Service ("Moody's") today assigned a rating of Baa3 to the proposed senior note issuance of Shire Acquisitions Investments Ireland Designated Activity Company (''Shire Acquisitions Investments Ireland DAC'' or ''SAIIDAC''), guaranteed by Shire plc ("Shire"). Moody's also affirmed Shire's existing ratings including the Baa3 issuer rating and the Baa3 rating on senior notes issued by Baxalta Incorporated ("Baxalta"), guaranteed by Shire. The rating outlook is stable.

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